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→Siehe auch
*[[PostVac]]
*[[PostVac]]
*[[Plötzlicher Tod nach Impfung gegen das neue Coronavirus]]
*[[Plötzlicher Tod nach Impfung gegen das neue Coronavirus]]
==Literatur==
*Jenna M. Benoit et al.: No evidence of immune exhaustion afterrepeated SARS-CoV-2 vaccination invulnerable and healthy populations, Nature Communications (2025) 16:5219, https://doi.org/10.1038/s41467-025-60216-3<br>Abstract: ''Frequent SARS-CoV-2 vaccination in vulnerable populations has raised con-cerns that this may contribute to T cell exhaustion, which could negativelyaffect the quality of immune protection. Herein, we examined the impact ofrepeated SARS-CoV-2 vaccination on T cell phenotypic and functionalexhaustion in frail older adults in long-term care (n = 23), individuals onimmunosuppressive drugs (n = 10), and healthy adults (n = 43), in Canada.Spike-specific CD4+ and CD8+ T cell levels did not decline in any cohort fol-lowing repeated SARS-CoV-2 vaccination, nor did the expression of exhaustionmarkers on spike-specific or total T cells increase. T cell production of multiplecytokines (i.e. polyfunctionality) in response to the spike protein of SARS-CoV-2 did not decline in any cohort following repeated vaccination. None of thecohorts displayed elevated levels of terminally differentiated T cells followingmultiple SARS-CoV-2 vaccinations. Thus, repeated SARS-CoV-2 vaccinationwas not associated with increased T cell exhaustion in older frail adults, immunosuppressed individuals, or healthy adults.''
==Bildbelege==
==Bildbelege==