Modifications

<ref>https://www.ncbi.nlm.nih.gov/pubmed/?term=Kuhn+M%2C+Grave+S%2C+Bransfield+R%2C+Harris+S Article "Long term antibiotic therapy may be an effective treatment for children co-morbid with Lyme disease and autism spectrum disorder", auteurs: Kuhn M, Grave S, Bransfield R, Harris S, publié en mai 2012 dans [[Medical Hypotheses]].<br>Abstract<br>Patients diagnosed with [[Maladie de Lyme|Lyme disease]] share many of the same physical manifestations as those diagnosed with an Autism Spectrum Disorder (ASD). In this study four male children (ages 26-55 months) who have an ASD diagnosis and one male child (age -O meets state and federal requirements for providing a comprehensive, ongoing assessment of a child with an ASD [33]. The SAP-O form measures children's abilities using observational, authentic assessment procedures in the domains of joint attention, symbol use, mutual regulation, and self regulation via observations of specific behaviors in familiar settings [33]. The five children tested positive for [[Maladie de Lyme|Lyme disease]] and their SAP-O score was evaluated before and after 6 months of antibiotic therapy. Each child was prescribed 200mg of amoxicillin three times per day and three of the five children were prescribed an additional 50mg of Azithromycin once per day. All of the children's scores on the SAP-O assessment improved after 6 months of antibiotic therapy. The assessors also reported anecdotal data of improved speech, eye contact, sleep behaviors, and a reduction of repetitive behaviors.</ref>

<ref>https://www.ncbi.nlm.nih.gov/pubmed/?term=Kuhn+M%2C+Grave+S%2C+Bransfield+R%2C+Harris+S Article "Long term antibiotic therapy may be an effective treatment for children co-morbid with Lyme disease and autism spectrum disorder", auteurs: Kuhn M, Grave S, Bransfield R, Harris S, publié en mai 2012 dans [[Medical Hypotheses]].<br>Abstract<br>Patients diagnosed with [[Maladie de Lyme|Lyme disease]] share many of the same physical manifestations as those diagnosed with an Autism Spectrum Disorder (ASD). In this study four male children (ages 26-55 months) who have an ASD diagnosis and one male child (age -O meets state and federal requirements for providing a comprehensive, ongoing assessment of a child with an ASD [33]. The SAP-O form measures children's abilities using observational, authentic assessment procedures in the domains of joint attention, symbol use, mutual regulation, and self regulation via observations of specific behaviors in familiar settings [33]. The five children tested positive for [[Maladie de Lyme|Lyme disease]] and their SAP-O score was evaluated before and after 6 months of antibiotic therapy. Each child was prescribed 200mg of amoxicillin three times per day and three of the five children were prescribed an additional 50mg of Azithromycin once per day. All of the children's scores on the SAP-O assessment improved after 6 months of antibiotic therapy. The assessors also reported anecdotal data of improved speech, eye contact, sleep behaviors, and a reduction of repetitive behaviors.</ref>

<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636014/ Article "Autism and Lyme Disease—Reply", auteurs: Mary Ajamian, MS, Anjali M. Rajadhyaksha, PhD, and Armin Alaedini, PhD, publié le 28 août 2013 dans JAMA.<br>In Reply<br>We evaluated the hypothesis that the rate of Lyme disease or associated seroprevalence is increased in children with autism as has been put forward by Dr Bransfield and others.1,2 A key assertion previously made in their Medical Hypotheses articles is that a substantial number of children with autism have active [[Maladie de Lyme|Lyme disease]], with associated symptoms presumably resolving through antibiotic treatment.1,2 However, Bransfield and Kuhn now instead suggest that [[Maladie de Lyme|Lyme disease]] triggered autism in the affected children’s distant past (ie, B burgdorferi infection was no longer present), citing that as a reason why seropositivity could not be detected in any of the autistic children that we studied. Such a claim is contradictory to their previous argument for the association of autism with ongoing and antibiotic-responsive B burgdorferi infection. [...]</ref>

Nous avons évalué l'hypothèse selon laquelle le taux de [[maladie de Lyme]] ou de séroprévalence associée est plus élevé chez les enfants autistes, comme l'ont avancé le Dr Bransfield et d'autres. Une affirmation clé déjà faite dans leurs articles sur les hypothèses médicales est qu'un nombre important d'enfants autistes présentent une [[maladie de Lyme]] active, avec symptômes associés probablement résolus par traitement antibiotique. Cependant, Bransfield et Kuhn suggèrent plutôt que la [[maladie de Lyme]] a déclenché l'autisme chez les enfants atteints dans un passé lointain (l'infection à B. burgdorferi n'était plus présente), citant cela comme raison pour laquelle la séropositivité ne pouvait être détectée chez aucun des enfants autistes que nous étudions. Une telle allégation est contradictoire avec leur argument précédent en faveur de l'association de l'autisme avec une infection à B. burgdorferi continue et sensible aux antibiotiques. [...]<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636014/ Article "Autism and Lyme Disease—Reply", auteurs: Mary Ajamian, MS, Anjali M. Rajadhyaksha, PhD, and Armin Alaedini, PhD, publié le 28 août 2013 dans JAMA.<br>In Reply<br>We evaluated the hypothesis that the rate of Lyme disease or associated seroprevalence is increased in children with autism as has been put forward by Dr Bransfield and others.1,2 A key assertion previously made in their Medical Hypotheses articles is that a substantial number of children with autism have active [[Maladie de Lyme|Lyme disease]], with associated symptoms presumably resolving through antibiotic treatment.1,2 However, Bransfield and Kuhn now instead suggest that [[Maladie de Lyme|Lyme disease]] triggered autism in the affected children’s distant past (ie, B burgdorferi infection was no longer present), citing that as a reason why seropositivity could not be detected in any of the autistic children that we studied. Such a claim is contradictory to their previous argument for the association of autism with ongoing and antibiotic-responsive B burgdorferi infection. [...]</ref>

<ref>https://law.justia.com/cases/new-jersey/appellate-division-published/2008/a3035-07-opn.html JEFFREY SHECTMAN v. ROBERT BRANSFIELD, M.D</ref>

<ref>https://law.justia.com/cases/new-jersey/appellate-division-published/2008/a3035-07-opn.html JEFFREY SHECTMAN v. ROBERT BRANSFIELD, M.D</ref>